I never had issues with my erection until I was 62. Even after taking a high-protein diet, my erection ditches me. So I was looking for Sildenafil brands which were high in cost. I found Zeagra 100mg on Trustmydrugs through an email link. They offered me the best price and told me that if it did not work, they would send another pill. Fortunately, it worked and I could sustain my erection for over 4 hours.
What is ZEAGRA 100MG?
Zeagra 100mg has an active ingredient, Sildenafil Citrate 100 mg. It is a phosphodiesterase type five (PDE 5) class of inhibitor. Its primary use is the treatment of erectile dysfunction (ED) or impotence in men between 18 and 64. It increases blood flow to the penile tissue to help achieve an erection in response to sexual arousal.
How Zeagra 100 mg Works
During sexual arousal, our body releases nitric oxide in the penile tissues to facilitate erection.
Nitric oxide activates the production of cyclic guanosine monophosphate (cGMP), which helps relax blood vessel walls in the penile region, allowing more blood flow into the penis.
PDE 5 hinders the erection process by breaking down cGMP. As a result, cGMP hydrolyzes, causing decreased cGMP levels. Sildenafil in Zeagra 100mg blocks and reduces the effects of the PDE5, helping cGMP levels to remain elevated and sustain the blood flow needed for an erection.
When the blood fills the erectile tissues (corpus cavernosum) in the penile area, it triggers a sturdy and long-lasting erection caused by an unabated blood flow.
What are the Uses and Benefits of ZEAGRA 100MG?
The medication helps men with ED by enhancing the natural process of arousal, enabling a firm and sustained erection when sexually stimulated.
Improvement of Sexual Performance
By supporting better blood flow, it may improve overall sexual satisfaction and performance.
Pulmonary Arterial Hypertension (off-label use)
Sildenafil, the active ingredient, is sometimes used to treat pulmonary arterial hypertension (high blood pressure in the lungs). However, this use typically requires a different dosage form and regimen, and it is essential to consult a doctor if this is the intended purpose.
Benefits of Zeagra 100 mg
Trusted Treatment
As an FDA-approved medication, Zeagra offers reliability and assurance for safe use when purchased from authentic sources.
Accessible in Various Quantities
It is available in various pack sizes, allowing flexibility based on individual needs.
Increased Confidence and Quality of Life
Reduced Anxiety
Men experiencing ED face anxiety and reduced self-confidence. By addressing the physical symptoms, Zeagra can reduce this anxiety, enhancing mental well-being.
Improved Relationships
With better sexual performance, many find that their intimate relationships also improve, fostering a stronger emotional connection with their partner.
Quick Action and Convenient Usage
Fast Onset
Zeagra usually starts working within 30-60 minutes, making it a convenient option for spontaneous use.
Long-Lasting Effect
Effects can last up to 4 hours, allowing for flexibility in timing sexual activity.
High Tolerance and Safety Profile
Reliable and Well-Studied
Sildenafil citrate is a widely studied medication, and its effects and safety profile are well-understood when taken as prescribed.
Mild Side Effects
The side effects are mild and manageable, making it a suitable choice for long-term use.
Off-Label Benefits for Pulmonary Arterial Hypertension
Doctors may prescribe Zeagra 100mg off-label usage for conditions like pulmonary arterial hypertension (PAH), as it relaxes blood vessels, reducing pressure and improving exercise tolerance.
What are the Safe Dosages of ZEAGRA 100MG?
Usage Instructions
Take Zeagra 100 mg 30-60 minutes before planned sexual activity, and its effects can last up to 4 hours.
Dosage
Typically, one Zeagra 100 mg tablet 30-60 minutes before sexual activity.
Frequency
One pill in 24 hours.
Standard Dosage
Zeagra 50 mg or 100 mg
Common Starting Dose
Zeagra 50 mg, taken approximately 30-60 minutes before sexual activity.
Higher Dose
A doctor may prescribe Zeagra 100 mg if the 50 mg dose is ineffective.
Lower Dosage: Zeagra 25 mg for older adults or beginners
Doctors may recommend Zeagra 25 mg for older adults with pre-existing health conditions or who are on medications that interact with Sildenafil.
Adjust Dose
Doctors use this lower dose to minimize the risk of side effects.
Maximum Frequency
Once per Day
Take one Zeagra pill once in 24 hours, regardless of the dosage.
Higher Dosage if Needed
If the 50 mg dose does not produce the desired effect and is well-tolerated, a doctor may increase the dosage to 100 mg.
Reducing Dose if Side Effects Occur
If a patient experiences side effects at a higher dose, a doctor may reduce the dosage to Zeagra 25mg.
Timing
For best results, take Zeagra on an empty stomach, as food can delay its onset of action.
How to take ZEAGRA 100MG?
Administration
Swallow the tablet whole with water. Avoid high-fat meals, as they can delay the effects.
Timing
Take the tablet approximately 30 to 60 minutes before planned sexual activity. It allows the medication time to be absorbed and start working.
Duration of Effect
The effects typically last up to 4 hours but may vary depending on individual response.
Administration
Swallow the tablet whole with a glass of water. Do not crush, chew, or break the tablet. It may affect how the body absorbs the drug.
With or Without Food
Empty Stomach
Zeagra works best when taken on an empty stomach, as food (especially high-fat meals) can delay its onset of action.
With Food
You can take it with food, but avoid heavy or fatty meals, which can delay the absorption.
Avoid Alcohol and grapefruit
Alcohol
Excessive Alcohol consumption can reduce the effectiveness and increase the risk of side effects.
Grapefruit
Avoid grapefruit or grapefruit juice, as it can interfere with the metabolism of the medication.
One-Dose per Day
Never take Zeagra 100mg more than once in 24 hours. Exceeding the recommended dosage can increase the risk of severe side effects.
Additional Considerations
Sexual arousal needed
Zeagra will not cause an erection on its own, but you need sexual stimulation for Zeagra 100mg to work effectively.
When Should I Avoid ZEAGRA 100MG?
Zeagra 100mg Disease Contraindications
Cardiovascular Conditions
Severe Heart Disease: Individuals with serious heart conditions, such as unstable angina, severe heart failure, or a recent history of a heart attack (myocardial infarction) or stroke, should avoid Zeagra.
High or Low Blood Pressure: Those with uncontrolled hypertension (high blood pressure) or severe hypotension (low blood pressure) must avoid taking Zeagra, as it can affect blood pressure levels.
Arrhythmias: Zeagra can be risky for people with severe arrhythmias (irregular heartbeats).
Liver and Kidney Disease
Severe Liver Disease: Patients with significant liver impairment, such as cirrhosis, may not metabolize the drug well, leading to increased side effects.
Severe Kidney Disease: Dosage adjustments may be necessary for patients with renal impairment.
Eye Disorders
Retinitis Pigmentosa: People with this genetic eye disorder must avoid using Zeagra, as it can affect retinal health.
Non-Arteritic Anterior Ischemic Optic Neuropathy (NAION): Those with a history of NAION, which causes sudden vision loss, should avoid the medication as it may increase the risk of optic nerve damage.
Blood-Related Disease
Bleeding Disorders: Zeagra may increase bleeding risk, so those with conditions like hemophilia should use it with caution.
Peptic Ulcers: People with active peptic ulcers or other bleeding issues should avoid Zeagra due to the potential for exacerbating bleeding.
Deformity of the Penis
Structural Penile Disorders: Men with conditions such as Peyronie’s disease (curved penis) or fibrous tissue formation should avoid Zeagra, as it may increase the risk of painful or prolonged erections (priapism).
Allergy to Sildenafil
Individuals with a known allergy to Sildenafil or any other ingredients in Zeagra should not take it.
Other Medications that Interact with Sildenafil
Nitrates
Individuals who are on nitrates (commonly used for chest pain) or nitric oxide donors must avoid Zeagra because the combination can cause a dangerous drop in blood pressure.
Certain Blood Pressure Medications
Specific antihypertensive drugs may interact with Sildenafil. Consult a doctor if you are taking blood pressure-lowering medications.
Other PDE5 Inhibitors
Avoid combining Zeagra with other PDE5 inhibitors, as it can increase the risk of side effects.
Zeagra 100mg Drug Contraindications
Nitrates
Examples: nitroglycerin, isosorbide mononitrate, isosorbide dinitrate (used for angina or chest pain)
Combining Zeagra with nitrates can cause a dangerous drop in blood pressure, potentially leading to fainting, heart attack, or stroke. Avoid oral nitrates and other forms (like sprays, patches, or ointments).
Nitric Oxide Donors
Examples: Sodium nitroprusside.
Like nitrates, these drugs can cause a severe drop in blood pressure when combined with Zeagra.
Alpha-Blockers
Examples: Doxazosin, prazosin, and tamsulosin (used to treat high blood pressure or prostate enlargement)
These medications also lower blood pressure, and using them with Zeagra can lead to symptomatic hypotension (dizziness, fainting). If prescribed together, there should be careful management of timing between the doses.
Other PDE5 Inhibitors
Examples: Tadalafil, vardenafil, avanafil.
Using more than one PDE5 inhibitor can increase the risk of adverse effects, especially hypotension and priapism (painful, prolonged erections).
Certain Antifungal Medications (CYP3A4 Inhibitors)
Examples: Ketoconazole, itraconazole.
These drugs can increase blood levels, raising the risk of side effects. Doctors may adjust the doses for combined usage under medical supervision.
Certain Antibiotics (CYP3A4 Inhibitors)
Examples: Erythromycin, clarithromycin.
The antibiotics inhibit the metabolism of Sildenafil, leading to higher drug concentrations and increased risk of side effects.
HIV Protease Inhibitors
Examples: Ritonavir, saquinavir.
These drugs can significantly increase sildenafil levels in the blood. If combined, doctors recommend a lower dose of Zeagra, but only under strict medical guidance.
Certain Hepatitis C Medications
Examples: Boceprevir, Telaprevir.
Hence, doctors may adjust the dose carefully and monitor the blood pressure levels because this medication, if administered alongside Zeagra 100mg, may increase blood pressure.
Antihypertensive Drugs
Examples: ACE inhibitors, beta-blockers, and calcium channel blockers.
While many antihypertensives are safe with Sildenafil, some may enhance the blood pressure-lowering effect, leading to hypotension.
What are the Side effects of ZEAGRA 100MG?
Common ZEAGRA 100MG Side Effects
Headache
It is the most common side effect, occurring as blood vessels dilate. Staying hydrated and taking over-the-counter pain relievers (if a doctor approves) can help.
Flushing
A sense of warmth, redness, or a tingling sensation, typically in the face, neck, or chest, because of increased blood flow and dilation of blood vessels.
Dizziness or Light-headedness
Some users may feel dizzy or lightheaded, especially when standing up. It is because of a mild drop in blood pressure, a common drug effect. Avoiding sudden movements and sitting or lying down if dizziness occurs can help.
Upset Stomach or Indigestion
It may include discomfort, bloating, or acid reflux. Taking Zeagra on an empty stomach can help reduce this side effect. Avoid heavy meals before taking the medication.
Nasal Congestion or Runny Nose
Some people may experience a stuffy or runny nose. It usually resolves naturally, but if persistent, nasal decongestants may help.
Visual Disturbances
Blurred vision, changes in color vision (a blue tinge to vision), or sensitivity to light because it affects blood flow to the eye and visual pathways in some people. These are short-lived; if persistent or bothersome, consult a doctor.
Back Pain or Muscle Pain
Mild to moderate pain in the back or muscles. Rest and over-the-counter pain relief (if approved by a doctor) can relieve these symptoms.
Nausea
Some individuals may feel slightly nauseous. Taking Zeagra with a light snack may help, although it may slow absorption.
Severe ZEAGRA 100MG side effects:
Priapism (Prolonged and Painful Erection)
An erection lasting over four hours does not go away. Priapism can lead to permanent damage to the penile tissue and long-term erectile dysfunction if not treated promptly. Seek immediate medical help if an erection lasts longer than 4 hours.
Sudden Vision Loss (Non-Arteritic Anterior Ischemic Optic Neuropathy or NAION)
Sudden, partial, or complete vision loss in one or both eyes may be irreversible, caused by reduced blood flow to the optic nerve. Stop the use and seek emergency medical attention if sudden vision changes occur.
Sudden Hearing Loss
A sudden decrease or loss of hearing with ear ringing (tinnitus) may be irreversible, so prompt action is crucial. Stop taking Zeagra immediately and contact a doctor if you experience any hearing changes.
Severe Allergic Reaction (Anaphylaxis)
Symptoms may include swelling of the face, lips, tongue, or throat, difficulty breathing, severe rash, or itching. Anaphylaxis is a life-threatening allergic reaction. Seek emergency medical attention if you experience any signs of a severe allergic reaction.
Chest Pain or Heart Attack Symptoms
Symptoms are chest pain, pressure, discomfort, pain radiating to the arm or jaw, sweating, and shortness of breath. Men with heart conditions are at higher risk, especially if they exert themselves during sexual activity. Stop the use immediately and seek medical help if you experience chest pain or symptoms of a heart attack.
Severe Dizziness or Fainting (Low Blood Pressure)
Extreme dizziness, feeling faint, or actual fainting episodes triggered by a significant drop in blood pressure, especially Zeagra combined with certain other medications (like nitrates or alpha-blockers). Sit or lie down if dizziness occurs, and seek medical help if symptoms persist.
Severe Skin Reactions
Rare but severe skin reactions can include blistering, peeling, or red, raw patches of skin. Zeagra may trigger conditions like Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN). Stop taking the medication immediately and seek medical help if severe skin reactions occur.
Severe Shortness of Breath or Swelling in the Legs (Pulmonary Hypertension or Heart Failure Symptoms)
Difficulty breathing, sudden shortness of breath, or swelling in the feet or legs could suggest fluid buildup or heart complications. Seek medical attention if these symptoms develop.
The best part is I get no side effects from Zeagra 100mg. I have tried many Sildenafil variants including the branded ones and all gave me strong headaches, flushing, heaviness in my chest, etc. But Zeagra gave me nasal congestion and mild headache which is manageable.