What is Vega 100mg?
Vega 100mg has an active ingredient, Sildenafil Citrate 100mg, to
treat erectile dysfunction (ED) or impotence in adult males. Vega 100 mg works by using
sildenafil citrate, which is a PDE5 inhibitor. It enhances blood flow to the penis by inhibiting
the PDE5 enzyme, which helps to produce an erection during sexual arousal.
Step-by-Step Vega 100mg Action Mechanism
Step 1: Sexual Stimulation Triggers Release of Nitric Oxide (NO)
When sexually aroused, our body naturally releases nitric oxide (NO) in the penile tissues to
increase blood flow for erection. It is the first step in enabling an erection.
Step 2: Increase in cGMP Levels
Nitric oxide stimulates the production of cyclic guanosine monophosphate (cGMP), a molecule that
relaxes smooth muscle cells in blood vessel walls. When cGMP levels increase, it causes blood
vessels to widen (vasodilation) in the erectile tissues (corpus cavernosum surrounding (on both
sides of) the penis.
Step 3: Enhanced Blood Flow
The blood vessel dilation facilitates an increased blood flow into the penile tissues,
specifically the corpora cavernosa (the spongy tissue that fills with blood to produce an
erection). This increased blood flow enables the penis to become firm, leading to an erection.
Inhibition of PDE5 Enzyme
Under normal conditions, the enzyme phosphodiesterase type 5 (PDE5) breaks down cGMP in the
erectile tissues, causing the blood vessels to constrict again. As a result, blood flow in the
erectile tissues will reduce, leading to a loss of the erection.
Sildenafil in Vega 100 mg inhibits the action of PDE5, allowing cGMP levels to remain elevated
for a longer duration. It prolongs the dilation of blood vessels, maintaining the erection.
Sustained Erection with Sexual Stimulation
By blocking PDE5, sildenafil helps maintain an erection enough for satisfactory sexual
intercourse. However, it only works in response to sexual arousal; it does not cause an erection
on its own.
What are the Uses and Benefits?
Vega 100 mg (sildenafil citrate) is primarily for erectile dysfunction (ED) treatment in men, but
it has additional therapeutic uses and benefits under medical supervision.
Treatment of Erectile Dysfunction (ED)
Vega 100 mg is highly effective in managing ED by improving blood flow to the penis. It helps men
achieve and sustain an erection during sexual activity.
Benefits:
- Enhances sexual performance and satisfaction
- Boosts self-confidence and reduces anxiety related to ED.
- Supports intimate relationships by improving sexual health.
Treatment of Pulmonary Arterial Hypertension (PAH)
Besides ED, sildenafil, the active ingredient in Vega 100 mg, can treat PAH, a condition of high
blood pressure in the lung arteries. By relaxing blood vessels, sildenafil reduces the workload
on the heart.
Benefits:
- Reduces symptoms such as shortness of breath, dizziness, and fatigue
- Improves exercise capacity and quality of life for people with PAH
Increased Exercise Capacity
Sildenafil increases oxygen supply in the blood, which can boost physical endurance and stamina,
particularly in those with PAH or low blood flow-related issues.
Benefits:
- Improves physical performance in certain medical conditions
- Supports better cardiovascular health and endurance under medical guidance
Effective Treatment for Erectile Dysfunction (ED)
- Proven Results: Sildenafil, the active ingredient in Vega 100 mg, is a
scientifically proven solution for most men with ED to achieve and maintain an erection
sufficient for sexual activity.
- Reliable and Fast-Acting: Vega 100mg typically starts working within 30-60
minutes, making it a convenient option for spontaneous or planned intimacy.
- Long-Lasting Effects: Vega 100mg can provide the ability to achieve an
erection for up to 4-6 hours, offering flexibility in timing.
Improved Sexual Confidence and Satisfaction
- Increased Confidence: Knowing you can achieve an erection when needed can
improve self-esteem, reduce anxiety, and enhance overall sexual confidence.
- Better Relationships: ED can place stress on relationships. Successfully
managing ED with Vega 100 mg can improve intimacy and strengthen your bond with your
partner.
- Reduced Performance Anxiety: For men who experience anxiety around
performance, this medication can eliminate concerns and improve overall enjoyment.
- Restored Quality of Life
- Regained Sense of Normalcy: ED can affect various aspects of mental health
and self-worth. Overcoming ED with Vega 100 mg can help bring back a sense of normalcy and
control over the body and life.
- Enhances Mental Health: By improving sexual function, Vega 100 mg can also
reduce feelings of frustration, embarrassment, or inadequacy often associated with ED.
Safe and Controlled When Prescribed
- Clinically Tested: The widely studied Sildenafil (Vega 100 mg active
ingredient) is an FDA-approved safe choice when used as directed.
- Non-Habit Forming: Unlike some medications, it does not lead to dependence,
and use it only as needed.
Improvement in Physical Endurance (if PAH is Present)
Treatment for PAH: Patients with pulmonary arterial hypertension (PAH) can
improve physical endurance and reduce symptoms like shortness of breath. However, a doctor may
suggest a specific dosing regimen.
When Should I Avoid Vega 100mg?
Individuals with certain health conditions (like severe heart problems or those taking nitrates)
should avoid this medication. Always consult a doctor before using it, as they can provide
proper guidance on safe usage and potential interactions.
Disease Contraindications
Severe Heart Disease
People with severe heart conditions, like heart failure, recent heart attack, or severe heart
valve disease, should avoid sildenafil. It is because sexual activity itself can strain the
heart and increase its workload, and sildenafil can further affect heart function.
Recent Heart Attack or Stroke
Individuals who have had a heart attack or stroke within the last 6 months should avoid using
sildenafil, as it can increase the risk of further complications.
Uncontrolled High or Low Blood Pressure
Sildenafil may interact with blood pressure, especially in those with severely high or low
levels.
Nitrate Medications
Medications containing nitrates (nitroglycerin, isosorbide dinitrate) for chest pain or heart
problems are a significant contraindication. The combination of sildenafil and nitrates can
cause a dangerous drop in blood pressure, leading to fainting, heart attack, or stroke.
Alpha-blockers for Hypertension or Prostate Problems
Sildenafil can interact with alpha-blockers, leading to low blood pressure. Doctors will monitor
the effects carefully or adjust the Vega dose.
Severe Liver or Kidney Disease
People with severe liver or kidney disease may not process sildenafil effectively, increasing the
risk of side effects. Doctors may recommend a lower dose or advise against use altogether.
Retinal Eye Disorders
Retinitis Pigmentosa
It is a rare genetic eye disease that gets worsened by PDE5 inhibitors like sildenafil,
potentially leading to vision impairment.
Non-Arteritic Anterior Ischemic Optic Neuropathy (NAION)
If you have a history of NAION, a condition that can cause sudden vision loss, avoid Vega 100mg,
as it may increase the risk of this condition reoccurring.
Severe Deformities of the Penis
Peyronie’s disease (a condition causing curvature of the penis) or other severe anatomical
deformities may increase the risk of injury when using Vega 100mg if one experiences a prolonged
erection.
Stomach Ulcers or Bleeding Disorders
People with active peptic ulcers or bleeding disorders, such as hemophilia, should use sildenafil
cautiously, as it can increase bleeding risk. If you have a history of these conditions, consult
your doctor before use.
Blood Cell Disorders
Conditions like sickle cell anemia, leukemia, and multiple myeloma may increase the risk of
priapism (prolonged and painful erection) when using sildenafil. Priapism is a medical emergency
that requires immediate treatment to prevent permanent damage.
Pulmonary Veno-Occlusive Disease (PVOD)
It is a rare lung condition where Vega 100mg can worsen the disease condition and lead to severe
complications.
Allergies to Sildenafil
If you have a known allergy to sildenafil or any ingredients in Vega 100 mg, you should not use
the medication.
Age-Related Precautions
Elderly individuals may be more sensitive to the effects of sildenafil and might require a lower
dose.
Drug Contraindications
Nitrates
Examples: nitroglycerin, isosorbide dinitrate, isosorbide mononitrate, and
certain recreational drugs like Poppers (amyl nitrate or butyl nitrate)
Doctors commonly prescribe nitrates for chest pain (angina) or heart conditions, and combining
them with sildenafil can lead to a severe and potentially life-threatening drop in blood
pressure. Avoid all nitrate medications if taking sildenafil. Even small amounts can lead to
significant side effects.
Alpha-Blockers
Examples: doxazosin, tamsulosin, alfuzosin, and prazosin (often used to treat
high blood pressure or prostate issues)
Alpha-blockers also lower blood pressure. When combined with sildenafil, there’s a
heightened risk of low blood pressure, dizziness, fainting, or even shock in extreme cases. If
alpha-blockers are necessary, Take Vega 100mg with extra caution and at a lower dose. However,
close monitoring by a healthcare provider is essential.
Other PDE5 Inhibitors
Examples: Tadalafil (Cialis), vardenafil (Levitra), and avanafil (Stendra)
Taking multiple PDE5 inhibitors together can significantly increase the risk of side effects such
as severe low blood pressure, vision problems, and prolonged erection (priapism). Never combine
sildenafil with another PDE5 inhibitor.
Antihypertensive Medications
Examples: Beta-blockers (metoprolol), calcium channel blockers (amlodipine), and
certain diuretics
While not always strictly contraindicated, combining sildenafil with these can lower blood
pressure further than intended, especially in those sensitive to blood pressure changes. Consult
a doctor to assess blood pressure stability before combining these drugs.
Protease Inhibitors for HIV/AIDS
Examples: Ritonavir, saquinavir, and other antiretroviral medications
Protease inhibitors cause a delay in drug metabolism and increase the drug levels in the
bloodstream. It can cause an increase in toxicity and side effects, such as low blood pressure,
dizziness, and priapism. Doctors advise a much lower dose and limit the frequency of intake.
Antifungal Medications
Examples: Ketoconazole, Itraconazole, and Voriconazole.
Antifungals can also slow down the metabolism of sildenafil, leading to higher-than-expected
levels in the bloodstream and a greater risk of side effects. You may need a lower Vega dose
when taking antifungal medications.
Antibiotics
Examples: Erythromycin and clarithromycin
Some antibiotics can affect the metabolism of Vega 100mg in the liver, leading to higher drug
levels and an increased risk of side effects. Dosage adjustments may be necessary alongside
antibiotic treatment while taking Vega 100mg.
Grapefruit and Grapefruit Juice
Grapefruit products can interfere with the enzymes that break down sildenafil, leading to
increased levels of the drug in the blood and the potential for more intense side effects. Avoid
grapefruit products while using sildenafil to prevent unintended side effects.
Blood Thinners and Anticoagulants
Examples: Warfarin, heparin, and newer anticoagulants like apixaban and
rivaroxaban
Although not directly contraindicated, sildenafil can increase the risk of bleeding in
individuals on blood thinners, especially if combined with other factors that raise bleeding
risk. Exercise caution, and if you notice any signs of unusual bleeding, immediately report it
to a doctor.
Medications that Prolong QT Interval
Examples: Certain antiarrhythmics (like amiodarone), antipsychotics, and some
antibiotics
Vega 100mg can impair heart rhythm, and when combined with drugs that also influence the QT
interval, it may increase the risk of irregular heartbeat. Consult a doctor, as combining these
may require caution or additional monitoring.
It works at its best every time I pop a pill Vega 100mg. I take thrice or more a week but give me one or two side effects which were manageable and mind. We (my wife and I) are happy with the product outcome.