I was having ED because of diabetes. I am 40 and have tried Sildenafil and Tadalafil separately but not together. Since I cannot take two ED pills concurrently because it will increase the workload of the heart, I took Sildalist 120 which serves my purpose. That is a rapid onset of action and is long-lasting. I don’t have to take another pill for erection for the next 2 days which makes me feel relaxed and I can do sex for the next two days.
Sildalist 120 Mg has a faster Onset and Long-Lasting Effect. The combination allows for quick action and sustained effects over an extended period. It offers enhanced flexibility. The presence of tadalafil provides a prolonged window for spontaneous sexual activity. It has an improved efficacy. Some combine the action of sildenafil and tadalafil for better results than using either separately.
What is Sildalist 120 mg?
Sildalist 120 mg provides an option for men who may benefit from a combination of sildenafil and tadalafil for treating ED. However, because of the potency of this combination, it is crucial to consult with a healthcare provider to ensure it is safe for you. Sildenafil Citrate 100 mg helps achieve an erection by increasing blood flow to the penis. It has a faster onset and typically lasts 4-6 hours. Tadalafil 20 mg has a longer duration of action and can last up to 36 hours.
Sildalist 120 mg is a dual-power medication, combining the effects of two active ingredients, sildenafil citrate and tadalafil. Both belong to a class of drugs known as PDE5 inhibitors. These drugs work together to increase blood flow to the penis, enabling an erection in response to sexual arousal.
When It Works, Sexual Stimulation Required
Sildalist 120 mg works when there is sexual arousal. It does not cause an erection on its own. It enhances the natural response to sexual stimulation.
Mechanism of Action of Sildenafil and Tadalafil
- Inhibition of PDE5 Enzyme: Both sildenafil and tadalafil block the enzyme phosphodiesterase type 5 (PDE5), which breaks down cyclic guanosine monophosphate (cGMP) in the penis.
- Increase in cGMP Levels: During sexual stimulation, our body releases nitric oxide (NO), which then leads to the production of cGMP. Higher cGMP levels relax the smooth muscle cells in the blood vessels of the penis, allowing them to widen (vasodilation) and improve blood flow to the area.
- Achieving an Erection: With enhanced blood flow, the penis becomes engorged, leading to an erection when sexually stimulated.
Sildenafil vs. Tadalafil in Sildalist 120 mg
- Sildenafil (100 mg): Because of its faster onset, sildenafil usually starts working within 30-60 minutes. It is effective for about 4-6 hours, which is suitable for a short period of sexual activity.
- Tadalafil (20 mg): Tadalafil has a much longer half-life, meaning it stays active in the body for up to 36 hours. It allows extended spontaneity over a longer period.
The Combined Effect of Sildalist
- Quick and Prolonged Action: Sildenafil provides a faster onset, helping you achieve an erection quickly, while tadalafil maintains the effect over a longer time, allowing for additional spontaneous erections during its duration.
- More Flexibility for Timing: This combination gives more flexibility compared to using sildenafil or tadalafil alone, as you do not have to time the dose as precisely and can enjoy spontaneous sexual activity for up to 36 hours after taking the pill.
What are the Uses and Benefits of Sildalist 120 mg?
Primary Use: Treatment of Erectile Dysfunction (ED)
- Enhanced Blood Flow to the Penis: Sildalist 120 mg increases blood flow to the penile tissues during sexual arousal, allowing men to achieve and maintain a firm erection.
- For Men with Difficulty Achieving or Sustaining an Erection: It is helpful for men who experience difficulty with erections because of physical or psychological factors, such as stress, anxiety, or underlying medical conditions.
Dual-Action for Fast and Prolonged Effect
- Rapid Onset with Sildenafil (100 mg): Sildenafil helps users achieve an erection within 30 to 60 minutes, making it suitable for spontaneous sexual activity.
- Extended Duration with Tadalafil (20 mg): Tadalafil provides a broader action window, with effects lasting up to 36 hours. It is especially beneficial for men who want more flexibility and spontaneity over a longer time.
Benefits of Sildalist 120 mg:
Increased flexibility and spontaneity
- Longer Duration: Unlike medications with only sildenafil, Sildalist has dual power sildenafil with tadalafil. Men can enjoy sexual activity more spontaneously, with no need for precise timing.
- Multiple Erections Possible: Since tadalafil lasts up to 36 hours, Sildalist can allow for several sessions of attaining erections during this period, as long as sexual stimulation is present.
Boosted Confidence and Relationship
- Improved Self-Confidence: Knowing that they can reliably achieve and maintain an erection helps many men feel more secure and less anxious about sexual performance.
- Enhanced Intimacy: By improving erectile function, a Sildalist 120 mg can help reduce strain in relationships, promote intimacy, and lead to a more satisfying sexual experience for both partners.
Higher Success Rate with Dual Power
- More Effective for Some Men: Some men find that the combination of sildenafil and tadalafil is more effective than either medication alone, particularly if they have not had ideal results with just one PDE5 inhibitor.
- Better Results for Severe ED: The combined action can provide better results for those with more severe erectile dysfunction or men who have not had the desired effect with single-ingredient ED medications.
Occasional or Frequent Use
- Adaptable Use: You can take Sildalist 120 mg as needed, whether for occasional or more regular use, as prescribed.
- Onset and Duration Coverage: With sildenafil for a quick start and tadalafil for an extended duration, the Sildalist 120 mg provides comprehensive coverage for sexual activity at different times throughout the day or evening.
What are the Safe Dosages of Sildalist 120 mg?
Because Sildalist 120 mg combines two potent drugs, it is essential to check with a doctor to ensure it is suitable for you, especially if you have heart issues, blood pressure concerns, or are taking medications that could interact with it.
Dosage: Take a Sildalist 120 mg 30-60 minutes before sexual activity, with effects lasting up to 36 hours.
Administration: Take one Sildalist tablet with water. Avoid alcohol and grapefruit juice, as these can interfere with the efficacy.
Duration of Effect: Sildenafil works within 30-60 minutes, and tadalafil maintains effectiveness for up to 36 hours.
One tablet per 24 hours: Take only one Sildalist tablet per 24 hours.
How to take the Sildalist 120 mg?
Heart Disease
Serious Heart Problems: If you have serious heart conditions, such as severe heart failure, arrhythmia, or unstable angina, the Sildalist 120 mg may increase heart strain, particularly during sexual activity.
Recent Heart Attack or Stroke: Avoid using Sildalist if you have had a heart attack or stroke within the past 6 months, as it can increase the risk of cardiovascular complications.
Use of Nitrate Medications
Nitrates for Chest Pain or Heart Issues: Avoid Medications containing nitrates (nitroglycerin, isosorbide dinitrate, or isosorbide mononitrate) with Sildalist 120 mg because combining these medications can cause a dangerous and severe drop in blood pressure.
Recreational Poppers (Amyl Nitrate or Butyl Nitrate): Avoid these substances because they have the same risk as prescription nitrates, and one must not combine them with the Sildalist 120 mg.
Uncontrolled High or Low Blood Pressure
Uncontrolled Hypertension (high blood pressure): If you have untreated or uncontrolled high blood pressure, taking Sildalist may increase the risk of complications.
Hypotension (low blood pressure): Sildalist 120 mg can cause further drops in patients with low blood pressure (hypotension), leading to dizziness, fainting, or even shock.
Severe Liver or Kidney Disease in patients
Advanced Liver or Kidney Problems: People with severe liver or kidney impairment may have trouble metabolizing the active ingredients in Sildalist, leading to an increased risk of side effects and toxicity.
Certain Eye Disorders
Retinitis Pigmentosa: This rare, inherited eye condition can worsen with PDE5 inhibitors like those in Sildalist, leading to potential vision impairment.
NAION (Non-Arteritic Anterior Ischemic Optic Neuropathy): If you have a history of NAION, which can cause sudden vision loss, avoid Sildalist as it may increase the risk of this condition recurring.
Severe Penile Conditions
Peyronie’s Disease: If you have severe penile deformities, these conditions increase the risk of priapism (prolonged erection). The Sildalist 120 mg may increase the risk of painful or prolonged erections that require medical attention.
Blood Disorders
Bleeding Disorders: If you have a bleeding disorder like hemophilia, a Sildalist 120 mg can increase the risk of bleeding and bruising.
Sickle Cell Anemia, Leukemia, or Multiple Myeloma: These conditions increase the risk of priapism (a prolonged and painful erection), which can be dangerous and require emergency treatment.
Combination with Other ED Medications
Other PDE5 Inhibitors: Avoid using Sildalist alongside other erectile dysfunction medications (e.g., tadalafil, vardenafil) as this can amplify side effects and increase the risk of complications, especially related to blood pressure and prolonged erections.
Certain Medications
Protease Inhibitors for HIV/AIDS: Medications such as ritonavir and saquinavir can increase the levels of sildenafil and tadalafil in the blood, heightening the risk of adverse effects.
Certain Antifungal and Antibiotic Medications: Medications like ketoconazole, itraconazole, erythromycin, and clarithromycin can also interfere with the breakdown of the Sildalist, increasing the likelihood of side effects.
Allergy to Sildenafil or Tadalafil
Allergic Reactions: If you have a known allergy to sildenafil or tadalafil, avoid Sildalist 120 mg to prevent a potential allergic reaction, which could include symptoms such as rash, itching, difficulty breathing, or swelling.
Grapefruit or Grapefruit Juice Consumption
Increased Side Effects: Grapefruit products interfere with the breakdown of Sildalist, leading to higher-than-normal drug levels in the bloodstream and increasing the risk of adverse effects.
Recreational Use or No ED Diagnosis
Not for Recreational Use: Sildalist is for men with a diagnosed condition of erectile dysfunction. Using it recreationally or without a legitimate need may lead to unnecessary side effects and health risks.
When Should I Avoid Sildalist 120 mg?
Heart Disease
Serious Heart Problems: If you have serious heart conditions, such as severe heart failure, arrhythmia, or unstable angina, the Sildalist 120 mg may increase heart strain, particularly during sexual activity.
Recent Heart Attack or Stroke: Avoid using Sildalist if you have had a heart attack or stroke within the past 6 months, as it can increase the risk of cardiovascular complications.
Use of Nitrate Medications
Nitrates for Chest Pain or Heart Issues: Avoid Medications containing nitrates (nitroglycerin, isosorbide dinitrate, or isosorbide mononitrate) with Sildalist 120 mg because combining these medications can cause a dangerous and severe drop in blood pressure.
Recreational Poppers (Amyl Nitrate or Butyl Nitrate): Avoid these substances because they have the same risk as prescription nitrates, and one must not combine them with the Sildalist 120 mg.
Uncontrolled High or Low Blood Pressure
Uncontrolled Hypertension (high blood pressure): If you have untreated or uncontrolled high blood pressure, taking Sildalist may increase the risk of complications.
Hypotension (low blood pressure): Sildalist 120 mg can cause further drops in patients with low blood pressure (hypotension), leading to dizziness, fainting, or even shock.
Severe Liver or Kidney Disease in patients
Advanced Liver or Kidney Problems: People with severe liver or kidney impairment may have trouble metabolizing the active ingredients in Sildalist, leading to an increased risk of side effects and toxicity.
Certain Eye Disorders
Retinitis Pigmentosa: This rare, inherited eye condition can worsen with PDE5 inhibitors like those in Sildalist, leading to potential vision impairment.
NAION (Non-Arteritic Anterior Ischemic Optic Neuropathy): If you have a history of NAION, which can cause sudden vision loss, avoid Sildalist as it may increase the risk of this condition recurring.
Severe Penile Conditions
Peyronie’s Disease: If you have severe penile deformities, these conditions increase the risk of priapism (prolonged erection). The Sildalist 120 mg may increase the risk of painful or prolonged erections that require medical attention.
Blood Disorders
Bleeding Disorders: If you have a bleeding disorder like hemophilia, a Sildalist 120 mg can increase the risk of bleeding and bruising.
Sickle Cell Anemia, Leukemia, or Multiple Myeloma: These conditions increase the risk of priapism (a prolonged and painful erection), which can be dangerous and require emergency treatment.
Combination with Other ED Medications
Other PDE5 Inhibitors: Avoid using Sildalist alongside other erectile dysfunction medications (e.g., tadalafil, vardenafil) as this can amplify side effects and increase the risk of complications, especially related to blood pressure and prolonged erections.
Certain Medications
Protease Inhibitors for HIV/AIDS: Medications such as ritonavir and saquinavir can increase the levels of sildenafil and tadalafil in the blood, heightening the risk of adverse effects.
Certain Antifungal and Antibiotic Medications: Medications like ketoconazole, itraconazole, erythromycin, and clarithromycin can also interfere with the breakdown of the Sildalist, increasing the likelihood of side effects.
Allergy to Sildenafil or Tadalafil
Allergic Reactions: If you have a known allergy to sildenafil or tadalafil, avoid Sildalist 120 mg to prevent a potential allergic reaction, which could include symptoms such as rash, itching, difficulty breathing, or swelling.
Grapefruit or Grapefruit Juice Consumption
Increased Side Effects: Grapefruit products interfere with the breakdown of Sildalist, leading to higher-than-normal drug levels in the bloodstream and increasing the risk of adverse effects.
Recreational Use or No ED Diagnosis
Not for Recreational Use: Sildalist is for men with a diagnosed condition of erectile dysfunction. Using it recreationally or without a legitimate need may lead to unnecessary side effects and health risks.
What are the Side effects of Sildalist 120 mg?
Common Sildalist 120 mg Side Effects
Common side effects of Sildalist 120 mg may include headache, flushing, dizziness, or upset stomach. Common side effects may include:
- Headache
- Flushing
- Dizziness
- Nasal congestion
- Stomach upset
- Blurry vision
- Nausea
- Back or muscle pain
- Diarrhea
- Indigestion
- Gastrointestinal discomfort
Severe Sildalist 120 mg Side Effects:
More severe side effects can occur, especially if you take Sildalist 120 mg with contraindicated medications or in those with certain medical conditions.
- Chest pain
- Priapism (painful erection lasting over 4 hours)
- Sudden decrease or loss in hearing or ringing (Tinnitus)
- Sudden decrease or loss in vision
- Severe dizziness or fainting
- Severe allergic reactions
- Breathlessness
- Heart problems
- Arrhythmia (irregular heartbeat or pounding)
- Blood pressure issues (severe drop in blood pressure)
Sildalist 120 mg gives me hardness every single time and I never miss it. People say ED pills are hit or miss. That is why I take the combo of sildenafil and tadalafil because if one does not work, the other will.