It is effective for Both Allergies & Asthma. Singulair Generic also prevents asthma symptoms like wheezing and breathing difficulties. Its Non-Drowsy Formula does not sedate users. It helps Exercise-Induced Asthma. People with asthma triggered by exercise benefit from Singulair. The medication is effective for Nasal Polyps & Chronic Sinusitis. Montelukast reduces inflammation-related nasal polyps, which antihistamines do not treat. It has no interaction with alcohol, unlike antihistamines. Montelukast does not have strong interactions with alcohol, making it safer for social drinking. It is FDA-Approved & Well-Tolerated.
What is Generic Singulair 10mg?
Generic Singulair (Montelukast) is a leukotriene receptor antagonist (LTRA). It blocks leukotrienes—inflammatory chemicals that cause:
- Airway constriction (tightness in the lungs)
- Mucus production (leading to congestion)
- Swelling & inflammation (causing asthma & allergy symptoms)
Step-by-Step Generic Singulair Mechanism of Action
Triggers of Inflammation
Allergens (pollen, dust, pet dander) or irritants (exercise, cold air) cause the body to release leukotrienes.
Leukotrienes Bind to Receptors
These chemicals attach to leukotriene receptors in the lungs & nasal passages, causing inflammation, swelling, and mucus buildup.
Montelukast Blocks the Receptors
Singulair Generic prevents leukotrienes from binding, stopping airway tightening and inflammation.
Symptoms Reduce
Airways remain open while breathing improves, and allergy symptoms like sneezing, runny nose, and congestion decrease.
Generic Singulair (Montelukast) Rapid Absorption
The body absorbs Montelukast rapidly after taking it orally.
10mg tablet Absorption
After administration of the 10-mg tablet to fasted adults, it reaches the mean peak Montelukast plasma concentration in 3 to 4 hours (Tmax). The mean oral bioavailability is 64%.
5mg chewable tablet Absorption
For the 5-mg chewable tablet, it reaches the mean Cmax in 2 to 2.5 hours after administration to adults in the fasted state. The mean oral bioavailability is 73% in the fasted state versus 63% when administered with a standard meal in the morning.
4mg chewable tablet Absorption
Singulair Generic reaches the mean Cmax 2 hours after administration of 4mg chewable tablet in pediatric patients 2 to 5 years of age in fasting.
What are the Uses and Benefits of Generic Singulair 10mg?
Uses Generic Singulair (Montelukast Sodium)
Asthma Prevention & Long-Term Control
Singulair Generic prevents wheezing, shortness of breath, and coughing caused by asthma. It is not a rescue inhaler but helps reduce asthma attacks.
Allergic Rhinitis (Seasonal & Perennial Allergies)
Singulair Generic treats sneezing, runny nose, congestion, and itchy eyes caused by pollen, dust, mold, or pet dander. It works when antihistamines alone are not enough.
Exercise-Induced Bronchoconstriction (EIB)
Singulair Generic helps prevent breathing difficulties triggered by exercise. Doctors recommend it to take at least 2 hours before exercise.
Nasal Polyps & Chronic Sinusitis (Off-Label Use)
Singulair Generic reduces inflammation in nasal passages, helping with long-term nasal congestion.
Benefits of Generic Singulair (Montelukast Sodium)
Once-Daily Convenience–Unlike inhalers or antihistamines requiring multiple doses, Montelukast is effective for 24 hours.
Non-Drowsy–Unlike older antihistamines (like Benadryl), it does not cause sleepiness.
Reduces Inflammation–Helps with conditions that antihistamines alone cannot fix.
Safe for Long-Term Use–FDA-approved for both adults & children (from 6 months old for allergies, 12 months for asthma).
No Significant Drug Interactions–You can use it alongside most allergy or asthma medications.
What are the Safe Dosages of Generic Singulair 10mg?
The doses of Generic Singulair are 4mg oral granules, 4mg chewable tablets, 5mg chewable tablets, and 10mg tablets.
Dosage of Generic Singulair (Montelukast Sodium)
Asthma (Daily Prevention Dose)
- Adults & Teens (15+ years): 10mg once daily, taken in the evening.
- Children (6-14 years): 5mg once daily, taken in the evening (chewable tablet).
- Children (1-5 years): 4mg once daily, taken in the evening (chewable tablet or granules).
Allergic Rhinitis (Seasonal & Perennial Allergies)
- Adults & Teens (15+ years): 10mg once daily. Take it any time during the day.
- Children (6-14 years): 5mg once daily, taken at any time during the day (chewable tablet).
- Children (2-5 years): 4mg once daily, taken at any time during the day (chewable tablet or granules).
Exercise-Induced Bronchoconstriction (EIB)
- Adults & Teens (15+ years): 10mg once daily, taken at least 2 hours before exercise.
Nasal Polyps (Off-Label Use)
- Adults: 10mg once daily. Take it any time during the day.
How to take Generic Singulair 10mg?
- Take Singulair Generic once daily, with or without food.
- Swallow the tablet whole with a glass of water.
- If using a chewable tablet, chew it before swallowing.
- For granules (for children): Mix with breast milk, formula, or soft food (applesauce, yogurt) and give within 15 minutes.
Best Time to Take It
- For Asthma: Doctors recommend evening.
- For Allergies: You can take it anytime.
- For Exercise-Induced Symptoms: Take at least 2 hours before activity.
Notes on How Do You Administer Generic SINGULAIR
Your doctor will prescribe how much and when to take it. Do not pause taking it or change it when you take it without talking with your doctor. You can take it with food or without food. If you or your child misses a dose, take the next dose at your regular time. Do not double doses at the same time.
For adults and children 12 months of age and older with asthma
Take Singulair Generic 1 time each day, in the evening. Continue to take SINGULAIR every day for as long as your doctor prescribes it, even if you have no asthma symptoms. Tell your doctor right away if your asthma symptoms get worse or if you need to use the rescue inhaler medicine more often for asthma attacks. Do not take the medication if you need relief right away from a sudden asthma attack. If you have an asthma attack, follow the instructions of your doctor to treat asthma attacks. Always have your rescue inhaler medicine with you for asthma attacks. Do not stop taking or lowering the dose of your other asthma medicines unless your doctor tells you to.
For patients 6 years of age and older for the prevention of exercise-induced asthma
Take Singulair Generic at least 2 hours before exercise. Always have the rescue inhaler medicine with you for asthma attacks. If you take it every day for chronic asthma or allergic rhinitis, do not take another dose to prevent exercise-induced asthma. Talk to your doctor about your treatment for exercise-induced asthma. Do not take double doses within 24 hours (1 day).
When Should I Avoid Generic Singulair 100mg or Use Generic Singulair 10mg Cautiously?
Avoid Generic Singulair (Montelukast) If:
You Are Allergic to Montelukast or Its Ingredients. Signs of an allergic reaction include rash, swelling, itching, difficulty breathing, or severe dizziness.
You Are Taking It for an Acute Asthma Attack
Singulair Generic is NOT a rescue medication—it does not work fast to stop a sudden asthma attack. Use a short-acting inhaler (like albuterol) instead.
You Have a History of Mental Health Issues
Montelukast may cause mood changes, depression, suicidal thoughts, aggression, and hallucinations in some people. Avoid if you have a history of severe anxiety, depression, or suicidal tendencies.
You Have Severe Liver Disease
The liver processes Montelukast. It may worsen liver conditions like cirrhosis or hepatitis.
Use Montelukast with Caution If:
You Are Pregnant or Breastfeeding
Montelukast is category B (no proven risk in humans, but limited studies). Consult your doctor before use.
You Have Phenylketonuria (PKU) (For Chewable Tablets)
Some chewable Montelukast tablets contain aspartame, which people with PKU must avoid.
You Are Using Other Asthma or Allergy Medications
While Montelukast is generally safe with other medications, always check for possible drug interactions.
You Experience Side Effects Like Severe Mood Changes or Hallucinations
Stop taking it and contact your doctor immediately.
Drug Interactions with Generic Singulair (Montelukast Sodium)
Medications That May Interact with Montelukast
Enzyme-Inducing Drugs (May Decrease Montelukast Effectiveness)
- Rifampin (Rifadin, Rimactane) → for tuberculosis (TB).
- Phenobarbital → for seizures and epilepsy.
- Phenytoin (Dilantin) → Another anti-seizure medication.
These drugs increase liver metabolism, reducing drug levels and making it less effective.
NSAIDs & Aspirin (May Worsen Asthma in Some Patients)
- Ibuprofen (Advil, Motrin)
- Naproxen (Aleve)
- Aspirin
In aspirin-sensitive asthma patients, NSAIDs can trigger bronchospasms, making asthma symptoms worse even while on Montelukast.
Corticosteroids (May Cause Overlapping Effects or Side Effects)
- Prednisone (Deltasone)
- Fluticasone (Flovent, Flonase)
- Budesonide (Pulmicort, Rhinocort)
These are also anti-inflammatory drugs used for asthma and allergies. Taking them with Montelukast may increase the risk of immune suppression or mood changes.
Mood-Altering Medications (May Increase Risk of Psychiatric Side Effects)
Antidepressants & Anxiety Meds
- Fluoxetine (Prozac)
- Sertraline (Zoloft)
- Paroxetine (Paxil)
Mood Stabilizers & Antipsychotics
- Lithium
- Risperidone (Risperdal)
Montelukast may cause mood changes, aggression, and suicidal thoughts. If you're taking these drugs, monitor for worsening depression or anxiety.
Medications That Are Safe to Take with Montelukast
- Antihistamines–Loratadine (Claritin), Cetirizine (Zyrtec), Fexofenadine (Allegra)–No known interactions.
- Inhalers–Albuterol (Ventolin), Salmeterol (Serevent), and Budesonide (Symbicort)–You can use it together.
- Decongestants–Pseudoephedrine (Sudafed), Oxymetazoline (Afrin)–safe.
What are the Side effects of Generic Singulair 10mg?
Common Generic Singulair 10mg Side Effects
- Headache (most frequently reported)
- Stomach pain or indigestion
- Diarrhea or nausea
- Tiredness or fatigue
- Fever (in children)
- Cough or cold-like symptoms
- Dizziness
- Heartburn
Severe Generic Singulair 10mg Side Effects
- Mental Health & Behavioral Changes (Most Serious Concern)
- Severe Allergic Reactions (Anaphylaxis – Life-Threatening)
- Liver Damage (Hepatotoxicity – Rare but Serious)
- Unusual Bleeding or Easy Bruising (Blood Disorders – Rare)
- Severe Skin Reactions (Rare but Life-Threatening)