Avanafil 50mg

Stendra and Spedra are the two prominent brands of Avanafil. It is a class of Phosphodiesterase type 5 inhibitors medications that help improve the blood flow in male genitals and cause hardness and erection to the male organ. The effect lasts a little longer (5-6 hours) than the other ED medications containing sildenafil (4 hours). It is more expensive than its counterparts because it does not have a generic version.

What is Avanafil 50mg?

Avanafil is a Phosphodiesterase type 5 inhibitors group of medications. It inhibits PDE 5 and slows it down for CGMP enzymes to flourish, and concentration increases in the erectile tissues. CGMP works as a vasodilator. The sheer increase in cGMP dilates (widens) the blood vessels in the penile area, causing improved blood supply. This increased blood supply in the erectile tissues causes a robust and sustainable erection, adequate for penetration, and enjoys long copulation, providing satisfaction to the partner.

What are the Uses and Benefits of Avanafil 50mg?

Avanafil 50mg Uses

It helps treat erectile dysfunction or impotence by causing quick erection when men need it fast. It helps attain rapid hardness to the penile organ. It is very effective in getting an erection regardless of health conditions. A study found that the medication improves the International Index of Erectile Function–Erectile Function (IIEF-EF), an index that provides a score to evaluate erection problems.

Avanafil showed marked improvement for all men at 50 to 200mg. The PDE-5 inhibitors class of medications improves blood supply by blocking PDE-5 enzymes and increasing cGMP concentration in the penile region. The enhanced blood flow in the penile erectile tissues causes a quick erection that is sustainable for 5-6 hours.

Avanafil 50mg Benefits:

• It facilitates erection by increasing blood flow in the erectile tissues of the penile region.
• The users achieve a robust, quick, and long-duration erection.
• It starts its effect in less than 15 minutes (Avanafil 100/200mg) and 30 minutes (Avanafil 50mg).
• It lasts a little longer (5-6 hours) than the other ED medications containing sildenafil (4 hours).
• Boost psychological state of mind and elevate the mood for sexual activity
• Eradicates psychological pressure caused by low self-esteem and fear of non-performance in bed
• Fosters the confidence and vigor in men

What are the Safe Dosages of Avanafil 50mg?

Typical safe doses are between 50-100 mg. Start with the lowest available, such as Avanafil 25mg. The safest dose is one your doctor prescribes. The starting dose is 50mg. Your doctor may increase the dosage to north of 100mg. Avanafil 50mg and lower may take up to 45 minutes to onset.

The online stores list the medication as Avanafil or Avana.

The common doses –

• Avanafil 50mg
• Avanafil 100mg
• Avanafil 200mg
• Top Avanafil
• Super Avanafil
• Extra Super Avanafil

It is a fast-acting erection pill for those who are in a short-notice sexual encounter and want to get in action in the blink of an eye. The medication dosage is one pill a day because it lingers in the bloodstream for 36 hours. Your doctor may alter the dosage as needed.

How to take Avanafil 50mg?

• It is an oral medication taken by the mouth.
• You can take the whole pill as a single dose in a day. Take it 15 minutes before the acts.
• The maximum dose is 200mg once a day.
• Swallow the whole pill with adequate water to facilitate absorption and assimilation and avoid dehydration.
• You can take it on an empty stomach, with or without meals.
• Avoid junk, oily, high-fat food. Take light meals before ingesting the drug.
• Do not crush, split, chew, or break it in the mouth.
• Never take more than one dose in 24 hours.
• Do not consume alcohol, smoke, drugs, substances, pre-existing medicines, or grape juice while taking it.

When Should I Avoid Avanafil 50mg or use it cautiously?

• Avoid using other PDE5 inhibitors used for erectile dysfunction, such as sildenafil, Tadalafil, or Vardenafil, or the brands Sildenafil, Cialis, or Levitra, when on Avanafil as it will cause an overdose and aggravate the side effects which could be dangerous for heart patients.
• A doctor goes through a detailed physical examination and medical history to determine the potential risk of using this erection remedy.
• You can give the ED remedy a miss if you fall under the conditions below-
• Use of any form of organic nitrate, including nitrates and nitrites
• Known hypertension and hypotension and consuming medications to treat the conditions
• Hypersensitivity to Avanafil or any component in the formulation may include Sildenafil, Tadalafil, and Vardenafil.

Cardiovascular effects

If you have pre-existing heart or cardiovascular diseases or heart blockage, stroke, heart attack, or heart surgery in the past six months, avoid this ED solution. If you have MI, arrhythmia, coronary revascularization, heart failure, resting hypotension, hypertension, unstable angina, or occurring during sexual activity, you must not take it.

Vasodilator agents

Avoid when using additive blood pressure lowering agents, such as antihypertensive drugs or alcohol, alpha-adrenergic agents, nitrate medications, or specific drugs and food that interact with Avanafil because it will dip the blood pressure to a dangerous level.

CYP3A4 inhibitors

Concomitant use of CYP3A4 inhibitors potentially increases the concentration of Avanafil. Your doctor needs to alter the dose to avoid such a condition. However, your physician will not recommend Avanafil in case of the concomitant use of CYP3A4 inhibitors.

Priapism (painful/prolonged erection)

You must stop taking the ED treatment if you have experienced Priapism, where the erection persists for over 4 hours, and a painful erection persists for over 6 hours. It may cause deformity of the penile organ or damaged tissues, leading to irreversible impotence. Underlying health conditions, such as sickle cell anemia, leukemia, multiple myeloma, patients with anatomic penile deformation, such as angulation, cavernosal fibrosis, and Peyronie’s disease, may predispose to Priapism and such patients must avoid the medication.

Ocular effects (vision disturbances)

Eye patients who experienced NAION (Non-arteritic anterior optic neuropathy) in one eye carry a potential risk of experiencing it in the other eye with the administration of PDE type 5 inhibitors. If you experience sudden loss or reduction of vision, discontinue the ED treatment and seek medical intervention. Visual disturbances, like blurred eye and color (blue/green) vision change, are rare with Avanafil 50mg.

Otic effects (loss of hearing)

Sudden decrease or loss of hearing and vestibular manifestation, such as dizziness and tinnitus, may occur with the medication. Avoid it under such underlying health conditions and concomitant administration of other ototoxic drugs.

Alpha-androgenic agents or alpha-blockers

Patients using such medications for hypotensive effects must use them with utmost caution if they are taking Avanafil. Your doctor may alter the dose or not recommend it for ED treatment.

Hematologic effects

Patients with a bleeding disorder or peptic ulcer must avoid it.

Hepatic/Renal impairment

For patients with severe hepatic (liver) or renal (kidney) impairment, renal dialysis must avoid it.

What are the Side effects of Avanafil 50mg?

Common Avanafil 50mg side effects

• Headache
• Nausea
• Facial Flushing
• Dizziness
• Stuffy nose, nasal congestion
• Back pain, muscle pain
• Pain in arm or leg
• Nasopharyngitis

Severe Avanafil 50mg side effects

• Chest pain
• Severe dizziness
• Breathlessness/shortness of breath
• Sudden hearing loss
• Sudden vision loss
• Priapism